What is Philadelphia-like-ALL?
- Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL), or BCR-ABL1-like ALL, is a high-risk subtype of B-cell precursor ALL characterized by a gene expression profile similar to Ph-positive ALL
- The frequency of Ph-like-ALL is 10-30% in Adults & 15% in Children
- Ph-like ALL markers are needed to assess whether adding tyrosine kinase inhibitors(TKIs) to current therapy will improve the survival of patients with this type of leukemia
Why you should order Ph-like-ALL?
Ph-like gene expressionshows higher riskof relapse
Decision to add Tyrosine Kinase Inhibitor (TKI)in current therapy
