Hotspot genes (SNVs and short indels): ALK, BRAF, EGFR, ERBB2, FGFR2, FGFR3, HRAS, KIT, KRAS, MAP2K1, MAP2K2, MET, MTOR, NRAS, PDGFRA, PIK3CA, RET and ROS1 Gene Fusions: ALK, BRAF, EGFR, ERBB2, FGFR2, FGFR3, MET, NTRK (1,2,3), PDGFRA, RET and ROS1 Copy number variation (CNV) genes: ALK, BRAF, EGFR, ERBB2, FGFR2, FGFR3, KIT, KRAS, MET, PDGFRA, PIK3CA and MYC